Mutations in the S gene region of hepatitis B virus genotype D in Golestan Province-Iran

@article{Moradi2012MutationsIT,
  title={Mutations in the S gene region of hepatitis B virus genotype D in Golestan Province-Iran},
  author={Abdolvahab Moradi and Sareh Zhand and Amir Ghaemi and Naeme Javid and Alijan Tabarraei},
  journal={Virus Genes},
  year={2012},
  volume={44},
  pages={382-387}
}
Mutations of HBsAg especially within the “a” determinant could alter the antigenicity of the protein causing failure of HBsAg neutralization and escaping from the host’s immune system, resulting in active viral replication and liver disease. This project aimed to investigate mutation in the S gene region of HBV infected patients in Golestan Province-Iran. HBV-DNA extractions from plasma and PCR of 100 patients were performed. Direct sequencing and alignment of S gene were applied using… CONTINUE READING

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References

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Showing 1-10 of 29 references

Hepatitis B virus surface antigen variants clustered within immune epitopes in chronic hepatitis B carriers from Hormozgan Province, south of Iran. Iran

  • M. Norouzi
  • J. Basic Med
  • 2010
Highly Influential
9 Excerpts

Mirmomen, Identification of HBV surface Ag variants in patients with hepatitis before and after immunization

  • M. Daram, R. Malekzadeh, Gh. Montazeri, S. M. Alavian, Sh
  • Govaresh 12(4),
  • 2008
Highly Influential
6 Excerpts

genotypes, subgenotypes, and HBsAg subtypes

  • H. Norder et al., Genetic diversity of hepatitis B virus strains derived worldwide
  • Intervirology 47, 289–309
  • 2004
Highly Influential
4 Excerpts

Prevalence of hepatitis B virus MHR mutations and their correlation with genotypes and antiviral therapy in chronically infected patients in Serbia

  • I. Lazarevic
  • J. Med. Virol
  • 2010
2 Excerpts

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