Mutations in a steroid hormone-regulated gene disrupt the metamorphosis of the central nervous system in Drosophila.

@article{Restifo1991MutationsIA,
  title={Mutations in a steroid hormone-regulated gene disrupt the metamorphosis of the central nervous system in Drosophila.},
  author={Linda L. Restifo and Kalpana White},
  journal={Developmental biology},
  year={1991},
  volume={148 1},
  pages={174-94}
}
The actions of steroid hormones on vertebrate and invertebrate nervous systems include alterations in neuronal architecture, regulation of neuronal differentiation, and programmed cell death. In particular, central nervous system (CNS) metamorphosis in insects requires a precise pattern of exposure to the steroid molting hormone 20-hydroxyecdysone (ecdysterone). To test whether the effects of steroid hormones on the insect nervous system are due to changes in patterns of gene expression, we… CONTINUE READING

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