Mutations in E coli cistrons affecting adhesion to human cells do not abolish Pap pili fiber formation.

@article{Norgren1984MutationsIE,
  title={Mutations in E coli cistrons affecting adhesion to human cells do not abolish Pap pili fiber formation.},
  author={Mari Norgren and Staffan J. Normark and D. T. Lark and P P O'Hanley and Gary K. Schoolnik and Stanley Falkow and Catharina Svanborg-Ed{\'e}n and Monica B{\aa}ga and Bernt Eric Uhlin},
  journal={The EMBO journal},
  year={1984},
  volume={3 5},
  pages={
          1159-65
        }
}
A chromosomal DNA fragment which mediates Pap (pili associated with pyelonephritis) pili formation, mannose-resistant hemagglutination ( MRHA ) and binding to uroepithelial cells has been isolated from the uropathogenic Escherichia coli clinical isolate J96 , and genetically studied. Analysis of polypeptides expressed by the Pap DNA led to detection of a number of polypeptides ranging in mol. wt. from 13 000 to 81 000 daltons. The gene order and transcriptional orientation for four of the… CONTINUE READING
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