Mutations in DSTYK and dominant urinary tract malformations.


BACKGROUND Congenital abnormalities of the kidney and the urinary tract are the most common cause of pediatric kidney failure. These disorders are highly heterogeneous, and the etiologic factors are poorly understood. METHODS We performed genomewide linkage analysis and whole-exome sequencing in a family with an autosomal dominant form of congenital… (More)
DOI: 10.1056/NEJMoa1214479


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