Mutations arising in the wave front of an expanding population.

@article{Edmonds2004MutationsAI,
  title={Mutations arising in the wave front of an expanding population.},
  author={Christopher A. Edmonds and Anita Lillie and Luca L. Cavalli-Sforza},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2004},
  volume={101 4},
  pages={
          975-9
        }
}
The ability to infer the time and place of origin of a mutation can be very useful when reconstructing the evolutionary histories of populations and species. We use forward computer simulations of population growth, migration, and mutation in an analysis of an expanding population with a wave front that advances at a constant slow rate. A pronounced founder effect can be observed among mutations arising in this wave front where extreme population bottlenecks arise and are followed by major… CONTINUE READING
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