Mutations and quantitative genetic variation: lessons from Drosophila.

@article{Mackay2010MutationsAQ,
  title={Mutations and quantitative genetic variation: lessons from Drosophila.},
  author={Trudy F C Mackay},
  journal={Philosophical transactions of the Royal Society of London. Series B, Biological sciences},
  year={2010},
  volume={365 1544},
  pages={1229-39}
}
A central issue in evolutionary quantitative genetics is to understand how genetic variation for quantitative traits is maintained in natural populations. Estimates of genetic variation and of genetic correlations and pleiotropy among multiple traits, inbreeding depression, mutation rates for fitness and quantitative traits and of the strength and nature of selection are all required to evaluate theoretical models of the maintenance of genetic variation. Studies in Drosophila melanogaster have… CONTINUE READING

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