Mutational spectra of benzo[a]pyrene and MeIQx in rpsL transgenic zebrafish embryos.

@article{Amanuma2002MutationalSO,
  title={Mutational spectra of benzo[a]pyrene and MeIQx in rpsL transgenic zebrafish embryos.},
  author={Kimiko Amanuma and Suguru Tone and Hotaka Saito and Tadayoshi Shigeoka and Yasunobu Aoki},
  journal={Mutation research},
  year={2002},
  volume={513 1-2},
  pages={83-92}
}
To evaluate the rpsL transgenic zebrafish (Brachydanio rerio) mutation assay, we treated the embryos with benzo[a]pyrene (B[a]P) (10 microg/ml) or 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) (300 microg/ml) for 16h and determined the mutation spectra. These treatments were previously reported to induce mutant frequencies that were 4.3 and 2.4… CONTINUE READING