• Corpus ID: 237267086

Mutational signatures and transmissibility of SARS-CoV-2 Gamma and Lambda variants

  title={Mutational signatures and transmissibility of SARS-CoV-2 Gamma and Lambda variants},
  author={Karen Y. Or'ostica and Sebasti{\'a}n Contreras and Sebastian B. Mohr and Jonas Dehning and Simone Bauer and David Medina-Ortiz and Emil N Iftekhar and Karen Mujica and Paulo C. Covarrubias and Soledad Ulloa and Andr{\'e}s E. Castillo and Ricardo A. Verdugo and Jorge Mozo Fern'andez and 'Alvaro Olivera-Nappa and Viola Priesemann},
The emergence of SARS-CoV-2 variants of concern endangers the long-term control of COVID-19, especially in countries with limited genomic surveillance. In this work, we explored genomic drivers of contagion in Chile. We sequenced 3443 SARS-CoV-2 genomes collected between January and July 2021, where the Gamma (P.1), Lambda (C.37), Alpha (B.1.1.7), B.1.1.348, and B.1.1 lineages were predominant. Using a Bayesian model tailored for limited genomic surveillance, we found that Lambda and Gamma… 

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