Mutational events after recurrent or chronic exposures of mutagenic and promutagenic N-nitroso compounds to a heterozygous tobacco tester strain

Abstract

Recurrent exposures (17 administrations in 37 days) to the direct-acting mutagens N-methyl-N-nitrosourea and N-ethyl-N-nitrosourea and a chronic exposure (38 days) to the metabolism-requiring mutagen dimethylnitrosamine markedly increased the frequency of somatic mutations in a double heterozygous chlorophyll mutant ofNicotiana tabacum, whereas exposure to N-methyl-N′-nitro-N-nitrosoguanidine was ineffective.

DOI: 10.1007/BF02894628

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Cite this paper

@article{Bza2008MutationalEA, title={Mutational events after recurrent or chronic exposures of mutagenic and promutagenic N-nitroso compounds to a heterozygous tobacco tester strain}, author={Jindřich Bř{\'i}za and Tom{\'a}{\vs} Gichner and Jiř{\'i} Velem{\'i}nsk{\'y} and Zdeněk Opatrn{\'y}}, journal={Biologia Plantarum}, year={2008}, volume={27}, pages={22-27} }