Mutational dynamics of the SARS coronavirus in cell culture and human populations isolated in 2003

@article{Vega2004MutationalDO,
  title={Mutational dynamics of the SARS coronavirus in cell culture and human populations isolated in 2003},
  author={Vinsensius B. Vega and Yijun Ruan and Jianjun Liu and Wah Heng Lee and Chia Lin Wei and Su Yun Se-Thoe and Kin Fai Tang and Tao Zhang and Prasanna R. Kolatkar and Eng Eong Ooi and Ai Ee Ling and Lawrence Walter Stanton and Philip M. Long and Edison T. Liu},
  journal={BMC Infectious Diseases},
  year={2004},
  volume={4},
  pages={32 - 32}
}
BackgroundThe SARS coronavirus is the etiologic agent for the epidemic of the Severe Acute Respiratory Syndrome. The recent emergence of this new pathogen, the careful tracing of its transmission patterns, and the ability to propagate in culture allows the exploration of the mutational dynamics of the SARS-CoV in human populations.MethodsWe sequenced complete SARS-CoV genomes taken from primary human tissues (SIN3408, SIN3725V, SIN3765V), cultured isolates (SIN848, SIN846, SIN842, SIN845… CONTINUE READING

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