Mutational analysis reveals separable DNA binding and trans-activation of Drosophila STAT92E.

@article{Karsten2006MutationalAR,
  title={Mutational analysis reveals separable DNA binding and trans-activation of Drosophila STAT92E.},
  author={Peter Karsten and Iris Plischke and Norbert Perrimon and Martin P Zeidler},
  journal={Cellular signalling},
  year={2006},
  volume={18 6},
  pages={819-29}
}
In the canonical model of JAK/STAT signalling STAT transcription factors are activated by JAK mediated tyrosine phosphorylation following pathway stimulation by external cytokines. Activated STAT molecules then homo- or heterodimerise before translocating to the nucleus where they bind to DNA sequences within the promoters of pathway target genes. DNA-bound STAT dimers then activate transcription of their targets via interaction with components of the basal transcription machinery. Here we… CONTINUE READING
18 Citations
20 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 18 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 20 references

B

  • S. Becker
  • Groner, C.W. Muller, Nature 394 (6689)
  • 1998
Highly Influential
4 Excerpts

C

  • R. Yan, S. Small
  • Desplan, C.R. Dearolf, J.E. Darnell Jr., Cell 84…
  • 1996
Highly Influential
4 Excerpts

S

  • H. Luo, P. Rose, D. Barber, W. P. Hanratty
  • Lee, T.M. Roberts, A.D. D’Andrea, C.R. Dearolf…
  • 2006

D

  • Z. L. Yuan, Y. J. Guan
  • Chatterjee, Y.E. Chin, Science 307 (5707)
  • 2005
1 Excerpt

MC Cell Biol

  • J. S. Rawlings, G. Rennebeck, S. M. Harrison, R. Xi, D. A. Harrison
  • 5 (1)
  • 2004
1 Excerpt

U

  • T. Meissner, E. Krause, I. Lödige
  • Vinkemeiwer, Cell 119 (5)
  • 2004
1 Excerpt

Cell Microbiol

  • M. Meister, M. Lagueux
  • 5 (9)
  • 2003
1 Excerpt

Dev

  • X. Chen, S. W. Oh, Z. Zheng, H. W. Chen, H. H. Shin, S. X. Hou
  • Cell 4 (2)
  • 2003

J

  • S. Brown, N. Hu
  • Castelli-Gair Hombrı́a, Development 130 (14)
  • 2003

Mech

  • J. Li, W. Li, H. C. Calhoun, F. Xia, F. B. Gao, W. X. Li
  • Dev. 120 (12)
  • 2003

Similar Papers

Loading similar papers…