Mutational analysis of the switch II loop of Dictyostelium myosin II.

@article{Sasaki1998MutationalAO,
  title={Mutational analysis of the switch II loop of Dictyostelium myosin II.},
  author={Nobuo Sasaki and Tsutomu Shimada and Kazuo Sutoh},
  journal={The Journal of biological chemistry},
  year={1998},
  volume={273 32},
  pages={
          20334-40
        }
}
A loop comprising residues 454-459 of Dictyostelium myosin II is structurally and functionally equivalent to the switch II loop of the G-protein family. The consensus sequence of the "switch II loop" of the myosin family is DIXGFE. In order to determine the functions of each of the conserved residues, alanine scanning mutagenesis was carried out on the Dictyostelium myosin II heavy chain gene. Examination of in vivo and in vitro motor functions of the mutant myosins revealed that the I455A and… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 32 CITATIONS

References

Publications referenced by this paper.

Mutations of the Switch II Loop of Myosin 20340 by gest on Sptem er 24

  • S. C. Gill, P. H. von Hippel
  • This article cites 34 references,
  • 1989
1 Excerpt

Similar Papers

Loading similar papers…