Mutational analysis of the BRCA2 gene in breast carcinoma patients of Kashmiri descent.

@article{Ayub2014MutationalAO,
  title={Mutational analysis of the BRCA2 gene in breast carcinoma patients of Kashmiri descent.},
  author={Shiekh Gazalla Ayub and Shabhat Rasool and Taha Ayub and Saquib Naveed Khan and Khursheed Alam Wani and Khurshid Iqbal Andrabi},
  journal={Molecular medicine reports},
  year={2014},
  volume={9 2},
  pages={749-53}
}
Breast cancer demonstrates geographical and ethnic variation in its incidence reflecting the effect of local environmental conditions and lifestyle. The genesis of the disease has further been complexed by the involvement of a number of genes with small effects and above all by population heterogeneity. Accordingly, variations in genes, including breast cancer 1, early onset (BRCA1)/breast cancer 2, early onset (BRCA2), that have been markedly associated with the breast cancer phenotype exhibit… CONTINUE READING