Mutational analysis of a DNA sequence involved in linking gene expression to the cell cycle.

@article{Andrews1992MutationalAO,
  title={Mutational analysis of a DNA sequence involved in linking gene expression to the cell cycle.},
  author={Brenda J. Andrews and L. And Daneo Moore},
  journal={Biochemistry and cell biology = Biochimie et biologie cellulaire},
  year={1992},
  volume={70 10-11},
  pages={
          1073-80
        }
}
Entry of budding yeast cells into the mitotic cell cycle requires the activity of a conserved regulatory kinase encoded by the CDC28 gene. The kinase is thought to trigger entry into the cell cycle or START, through association with a number of regulatory subunits known as G1 cyclins. A number of genes whose transcription is dependent on CDC28 and thus linked to START are controlled by two transcription factors, SWI4 and SWI6. The genes controlled by SWI4 and SWI6 include two known G1 cyclins… CONTINUE READING
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