Mutational analysis of 16S and 23S rRNA genes of Thermus thermophilus.

  title={Mutational analysis of 16S and 23S rRNA genes of Thermus thermophilus.},
  author={Steven T. Gregory and Jennifer F. Carr and Daniel T Rodriguez-Correa and Albert E. Dahlberg},
  journal={Journal of bacteriology},
  volume={187 14},
Structural studies of the ribosome have benefited greatly from the use of organisms adapted to extreme environments. However, little is known about the mechanisms by which ribosomes or other ribonucleoprotein complexes have adapted to functioning under extreme conditions, and it is unclear to what degree mutant phenotypes of extremophiles will resemble those of their counterparts adapted to more moderate environments. It is conceivable that phenotypes of mutations affecting thermophilic… CONTINUE READING