Mutational analysis and properties of the msbA gene of Escherichia coli, coding for an essential ABC family transporter

@article{Polissi1996MutationalAA,
  title={Mutational analysis and properties of the msbA gene of Escherichia coli, coding for an essential ABC family transporter},
  author={Alessandra Polissi and Costa Georgopoulos},
  journal={Molecular Microbiology},
  year={1996},
  volume={20}
}
The htrB gene was discovered because its insertional inactivation interfered with Escherichia coli growth and viability at temperatures above 32.5°C, as a result of accumulation of phospholipids. The msbA gene was originally discovered because when cloned on a low‐copy‐number plasmid vector it was able to suppress the temperature‐sensitive growth phenotype of an htrB null mutant as well as the accumulation of phospholipids. The msbA gene product belongs to the superfamily of ABC transporters, a… Expand
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TLDR
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