Mutational analysis (c.402C>G) of the FOXL2 gene and immunohistochemical expression of the FOXL2 protein in testicular adult type granulosa cell tumors and incompletely differentiated sex cord stromal tumors.

Abstract

BACKGROUND Recently a somatic point mutation in the FOXL2 gene has been characterized in ovarian adult type of granulosa cell tumor (ATGCT) (94.6%), thecomas (12.5%), but not in juvenile type of ovarian granulosa cell tumor, other ovarian sex cord tumors and ovarian surface epithelial neoplasms. Whether this mutation is present in testicular ATGCT or… (More)
DOI: 10.1097/PAI.0b013e3182039ef2

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@article{Hes2011MutationalA, title={Mutational analysis (c.402C>G) of the FOXL2 gene and immunohistochemical expression of the FOXL2 protein in testicular adult type granulosa cell tumors and incompletely differentiated sex cord stromal tumors.}, author={Ondřej Hes and Tom{\'a}{\vs} Vaně{\vc}ek and Fredrik Petersson and Petr Grossmann and M. S. Hora and Delia M Perez Montiel and Petr {\vS}teiner and Miroslav Dvoř{\'a}k and Michael Michal}, journal={Applied immunohistochemistry & molecular morphology : AIMM}, year={2011}, volume={19 4}, pages={347-51} }