Mutation-selection balance, dominance and the maintenance of sex.

  title={Mutation-selection balance, dominance and the maintenance of sex.},
  author={Jeffrey R. Chasnov},
  volume={156 3},
A leading hypothesis for the evolutionary function of sex postulates that sex is an adaptation that purges deleterious mutations from the genome, thereby increasing the equilibrium mean fitness of a sexual population relative to its asexual competitor. This hypothesis requires two necessary conditions: first, the mutation rate per genome must be of order one, and, second, multiple mutations within a genome must act with positive epistasis, that is, two or more mutations of different genes must… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.


Publications citing this paper.
Showing 1-10 of 23 extracted citations


Publications referenced by this paper.
Showing 1-10 of 10 references

The effect of variation on fitness

  • J. B. S. Haldane
  • Am . Nat . Press , Cambridge , UK .
  • 1937
Highly Influential
2 Excerpts

The muddle about muta46 – 52 . tions

  • J. R. Peck
  • Nature
  • 1997

Is a little bit of sex as good haploid and diploid phases

  • R. F. Green, D. L. G. Noakes
  • BioEssays J . Theor . Biol .
  • 1995

Similar Papers

Loading similar papers…