• Corpus ID: 86992274

Mutation screen of pulmonary myocardium development gene pituitary homeobox 2 in Chinese patients with isolated atrial fibrillation

@article{Yigan2011MutationSO,
  title={Mutation screen of pulmonary myocardium development gene pituitary homeobox 2 in Chinese patients with isolated atrial fibrillation},
  author={Li Yigan},
  journal={Shanghai Medical Journal},
  year={2011}
}
  • Li Yigan
  • Published 2011
  • Medicine, Biology
  • Shanghai Medical Journal
Objective To screen for the mutations of pituitary homeobox 2(PITX2) gene in Chinese patients with isolated atrial fibrillation and analyze the corresponding clinical characteristics of PITX2 variations.Methods A total of 16 patients with isolated atrial fibrillation and 200 age-matched healthy control subjects were enrolled in the present study.Exons of PITX2 gene were firstly amplified by RT-PCR,and the PCR products were screened by single strand conformation polymorphism analysis;the…