Mutation of the myosin converter domain alters cross-bridge elasticity.

@article{Khler2002MutationOT,
  title={Mutation of the myosin converter domain alters cross-bridge elasticity.},
  author={Jan K{\"o}hler and G. Winkler and Imke Schulte and Tim Scholz and William McKenna and Bernhard Brenner and Torsten Kraft},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2002},
  volume={99 6},
  pages={
          3557-62
        }
}
Elastic distortion of a structural element of the actomyosin complex is fundamental to the ability of myosin to generate motile forces. An elastic element allows strain to develop within the actomyosin complex (cross-bridge) before movement. Relief of this strain then drives filament sliding, or more generally, movement of a cargo. Even with the known crystal structure of the myosin head, however, the structural element of the actomyosin complex in which elastic distortion occurs remained… CONTINUE READING

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