Mutation of the S and 3c genes in genomes of feline coronaviruses

@inproceedings{Oguma2018MutationOT,
  title={Mutation of the S and 3c genes in genomes of feline coronaviruses},
  author={Keisuke Oguma and Megumi Ohno and Mayuko Yoshida and Hiroshi Sentsui},
  booktitle={The Journal of veterinary medical science},
  year={2018}
}
Feline coronavirus (FCoV) is classified into two biotypes based on its pathogenicity in cats: a feline enteric coronavirus of low pathogenicity and a highly virulent feline infectious peritonitis virus. It has been suspected that FCoV alters its biotype via mutations in the viral genome. The S and 3c genes of FCoV have been considered the candidates for viral pathogenicity conversion. In the present study, FCoVs were analyzed for the frequency and location of mutations in the S and 3c genes… CONTINUE READING
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