Mutation of low affinity nerve growth factor receptor gene in spontaneously hypertensive and stroke-prone spontaneously hypertensive rats: one of the promising candidate genes for hypertension.

@article{Nemoto1994MutationOL,
  title={Mutation of low affinity nerve growth factor receptor gene in spontaneously hypertensive and stroke-prone spontaneously hypertensive rats: one of the promising candidate genes for hypertension.},
  author={Kiyomitsu Nemoto and Haruaki Kageyama and Takeshi Hagiwara and Fumi Tashiro and Takako Tomita and I. N. Tomita and Takuzo Hano and Ichiro Nishio and Takashi Ueyama},
  journal={Brain research},
  year={1994},
  volume={655 1-2},
  pages={267-70}
}
There is evidence that abnormal formation of the sympathetic nervous system might be important for pathogenesis of hypertension. In the present study we analyzed nucleotide sequences of low affinity nerve growth factor receptor (LNGFR) genes in the spontaneously hypertensive rat and its stroke-prone substrain. There was a point mutation generating an amino… CONTINUE READING