Mutation of a bHLH transcription factor allowed almond domestication

  title={Mutation of a bHLH transcription factor allowed almond domestication},
  author={Raquel S{\'a}nchez-P{\'e}rez and Stefano Pavan and Rosa Mazzeo and C. Moldovan and Riccardo Aiese Cigliano and Jorge Del Cueto and Francesca Ricciardi and Concetta Lotti and L. Ricciardi and Federico Dicenta and Rosa Laura L{\'o}pez-Marqu{\'e}s and B Lindberg M{\o}ller},
  pages={1095 - 1098}
How to make almonds palatable The domesticated almond tree has been feeding humans for millennia. Derivation from the wild, bitter, and toxic almond required loss of the cyanogenic diglucoside amygdalin. Sánchez-Pérez et al. sequenced the almond genome and analyzed the genomic region responsible for this shift. The key change turned out to be a point mutation in a transcription factor that regulates production of P450 monooxygenases in the biosynthetic pathway for the toxic compound. Science… 
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  • K. Shirasawa, K. Isuzugawa, S. Isobe
  • Biology, Medicine
    DNA research : an international journal for rapid publication of reports on genes and genomes
  • 2017
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