Mutation of a bHLH transcription factor allowed almond domestication

@article{SnchezPrez2019MutationOA,
  title={Mutation of a bHLH transcription factor allowed almond domestication},
  author={R. S{\'a}nchez-P{\'e}rez and S. Pavan and R. Mazzeo and C. Moldovan and R. Aiese Cigliano and J. Del Cueto and F. Ricciardi and C. Lotti and L. Ricciardi and F. Dicenta and R. L. L{\'o}pez-Marqu{\'e}s and B. M{\o}ller},
  journal={Science},
  year={2019},
  volume={364},
  pages={1095 - 1098}
}
How to make almonds palatable The domesticated almond tree has been feeding humans for millennia. Derivation from the wild, bitter, and toxic almond required loss of the cyanogenic diglucoside amygdalin. Sánchez-Pérez et al. sequenced the almond genome and analyzed the genomic region responsible for this shift. The key change turned out to be a point mutation in a transcription factor that regulates production of P450 monooxygenases in the biosynthetic pathway for the toxic compound. Science… Expand
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