Mutation of Kisspeptin 1 Gene in Children with Precocious Puberty in Isfahan City

@inproceedings{Mazaheri2015MutationOK,
  title={Mutation of Kisspeptin 1 Gene in Children with Precocious Puberty in Isfahan City},
  author={Ali Mazaheri and Mahin Hashemipour and Mansoor Salehi and Mehdieh Behnam and Silva Hovsepian and Akbar Hassanzadeh},
  booktitle={International journal of preventive medicine},
  year={2015}
}
BACKGROUND Considering the role of kisspeptin (KISS) in the process of puberty, this study aimed to determine the mutation of KISS1 gene among a group of patients with idiopathic central precocious puberty (ICPP). METHODS In this case control study, a group of children with diagnosed ICPP and a group of healthy children were selected. Genomic DNA was extracted from peripheral blood of selected population. After proving the quality and quantity of extracted DNA samples by nano-drop instrument… CONTINUE READING
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