Mutation load under vegetative reproduction and cytoplasmic inheritance.

@article{Kondrashov1994MutationLU,
  title={Mutation load under vegetative reproduction and cytoplasmic inheritance.},
  author={Alexey S. Kondrashov},
  journal={Genetics},
  year={1994},
  volume={137 1},
  pages={311-8}
}
For reasons that remain unclear, even multicellular organisms usually originate from a single cell. Here I consider the balance between deleterious mutations and selection against them in a population with obligate vegetative reproduction, when every offspring is initiated by more than one cell of a parent. The mutation load depends on the genomic deleterious mutation rate U, strictness of selection, number of cells which initiate an offspring n, and the relatedness among the initial cells. The… CONTINUE READING

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