Mutation induced by drying of Escherichia coli on a hydrophobic filter membrane.

@article{Asada1980MutationIB,
  title={Mutation induced by drying of Escherichia coli on a hydrophobic filter membrane.},
  author={Shuji Asada and Mikihisa Takano and I Shibasaki},
  journal={Applied and environmental microbiology},
  year={1980},
  volume={40 2},
  pages={274-81}
}
Drying of Escherichia coli to a required cellular water level was conducted on a hydrophobic membrane at the corresponding relative humidity. Mutation from an arginine auxotroph to the prototroph was induced by drying to a water activity (aw) of 0.53 and below, but not to an aw of 0.75 and above. The critical aw below which mutation occurred in the course of drying was similar to that for induction of deoxyribonucleic acid (DNA) strand breakage in the bacteria. Some ultraviolet or gamma… CONTINUE READING