Mutation in TET2 in myeloid cancers.

Abstract

BACKGROUND The myelodysplastic syndromes and myeloproliferative disorders are associated with deregulated production of myeloid cells. The mechanisms underlying these disorders are not well defined. METHODS We conducted a combination of molecular, cytogenetic, comparative-genomic-hybridization, and single-nucleotide-polymorphism analyses to identify a… (More)
DOI: 10.1056/NEJMoa0810069

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