Mutation covariation of HIV-1 CRF07_BC reverse transcriptase during antiretroviral therapy.

@article{Li2013MutationCO,
  title={Mutation covariation of HIV-1 CRF07_BC reverse transcriptase during antiretroviral therapy.},
  author={Zhenpeng Li and Yang Huang and Yabo Ouyang and Hui Xing and Lingjie Liao and Shibo Jiang and Yiming Shao and Liying Ma},
  journal={The Journal of antimicrobial chemotherapy},
  year={2013},
  volume={68 11},
  pages={2521-4}
}
OBJECTIVES To understand the effect of HIV-1 drug resistance mutations in the context of antiretroviral therapy (ART), we compared the prevalence of protease (PR) and reverse transcriptase (RT) mutations in HIV-1 CRF07_BC sequences from blood samples of treatment-naive and ART-treated patients. METHODS Mutation covariation in the RT and PR of HIV-1 CRF07_BC viruses from 542 treatment-naive patients and 261 patients treated with lamivudine/zidovudine/nevirapine or lamivudine/zidovudine… CONTINUE READING