Mutation and inactivation of cultured mammalian cells exposed to beams of accelerated heavy ions. II. Chinese hamster V79 cells.

@article{Thacker1979MutationAI,
  title={Mutation and inactivation of cultured mammalian cells exposed to beams of accelerated heavy ions. II. Chinese hamster V79 cells.},
  author={John Thacker and Allan W. Stretch and M. A. Stephens},
  journal={International journal of radiation biology and related studies in physics, chemistry, and medicine},
  year={1979},
  volume={36 2},
  pages={137-48}
}
Inactivation and mutation to thioguanine-resistance of V79 hamster cells were studied after irradiation with accelerated helium, boron or nitrogen ions covering a range of linear energy transfer from 28 to 470 keV micrometers-1. For all radiation qualities a dose-dependent increase in mutant frequency was found for doses giving surviving fractions greater than about 0.20. The effectiveness per unit dose for both inactivation and mutation induction increased with the linear energy transfer of… CONTINUE READING

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