Mutated genes, pathways and processes in tumours

@article{Baudot2010MutatedGP,
  title={Mutated genes, pathways and processes in tumours},
  author={Ana{\"i}s Baudot and Victor de la Torre and Alfonso Valencia},
  journal={EMBO Reports},
  year={2010},
  volume={11},
  pages={805 - 810}
}
Integration of the many available sources of cancer gene information—such as large‐scale tumour‐resequencing studies— identifies the ‘usual suspect’ genes, mutated in many tumour types, as well as different sets of mutated genes according to the specific tumour type. Scaling‐up the analysis reveals that this large collection of mutated genes cluster into a smaller number of signalling pathways and processes. From this, we draw a map of the altered processes, and their combinations, in more than… 
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