Mutant kinesin-2 motor subunits increase chromosome loss.

@article{Miller2005MutantKM,
  title={Mutant kinesin-2 motor subunits increase chromosome loss.},
  author={Mark S Miller and Jessica M. Esparza and Andrew M. Lippa and Fordyce G Lux and Douglas G. Cole and Susan K. Dutcher},
  journal={Molecular biology of the cell},
  year={2005},
  volume={16 8},
  pages={
          3810-20
        }
}
The Chlamydomonas anterograde intraflagellar transport motor, kinesin-2, is isolated as a heterotrimeric complex containing two motor subunits and a nonmotor subunit known as kinesin-associated polypeptide or KAP. One of the two motor subunits is encoded by the FLA10 gene. The sequence of the second motor subunit was obtained by mass spectrometry and sequencing. It shows 46.9% identity with the Fla10 motor subunit and the gene maps to linkage group XII/XIII near RPL9. The temperature-sensitive… CONTINUE READING

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