• Biology
  • Published 1997

Mutant human α7 acetylcholine receptor subunits and their production and use

@inproceedings{1997MutantH,
  title={Mutant human α7 acetylcholine receptor subunits and their production and use},
  author={ゴパラクリシナン,ムラリ and サリバン,ジエイムズ・ピイ and トウマ,エドワード and ブリツグス,クラーク・エイ and マツケナ,デイビツド・ジイ and モンテツジア,リーサ・エム and ロツシユ,ジヤン−マルク},
  year={1997}
}
(57) Abstract: providing a mutant human α7 nicotinic acetylcholine receptor (nAChR) a polypeptide containing the amino acid substitutions at positions valine 274 of wild-type human alpha 7 nAChR. Nucleic acid encoding the mutant human α7nAChR molecules, also vectors and host cells containing such nucleic acid molecules provided. Also provides method for producing the variant, and methods of using such variants to screen compounds for activity in nAChR.