Mutagenicity testing of selected analgesics in Ames Salmonella strains.

Abstract

Acetaminophen (APAP), aspirin (ASA), phenacetin (PA) and ibuprofen (IB) were tested for mutagenic activity in the Ames Salmonella plate incorporation assay using strains TA98, TA100, TA1535, TA1537 and TA1538. These analgesics were tested in four separate tests: without metabolic activation, and in the presence of a rat, hamster or mouse liver post… (More)

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Cite this paper

@article{Oldham1986MutagenicityTO, title={Mutagenicity testing of selected analgesics in Ames Salmonella strains.}, author={James W. Oldham and Robert F. Preston and John David Paulson}, journal={Journal of applied toxicology : JAT}, year={1986}, volume={6 4}, pages={237-43} }