Mutagenicity of structurally related aromatic amines in the Salmonella/mammalian microsome test with various S-9 fractions.

@article{Shahin1983MutagenicityOS,
  title={Mutagenicity of structurally related aromatic amines in the Salmonella/mammalian microsome test with various S-9 fractions.},
  author={Majdi M. Shahin and Claude Chopy and Milagro Mayet and N Lequesne},
  journal={Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association},
  year={1983},
  volume={21 5},
  pages={
          615-9
        }
}
  • M. Shahin, C. Chopy, +1 author N. Lequesne
  • Published 1 October 1983
  • Biology, Medicine
  • Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
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TLDR
The mutagenicity of phenylazo-3-pyrzdines, like monocyclic aromatic amines and azo dyes, is influenced by the nature of the substifuent chemical groups and their positions in the molecular structure of the compounds.
Comparisons of mutation induction by six monocyclic aromatic amines in Salmonella typhimurium tester strains TA97, TA1537, and TA1538.
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The effect of metabolic transformation of the monoterpenes Linalool (Lin), Myrcene (Myr) and Eucalyptol (Euc) was evaluated on their antimutagenic potential against t-butyl hydroperoxide (t-BOOH)
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References

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Collaborative studies on the Salmonella/microsome mutagenicity assay.
  • V. Dunkel
  • Chemistry, Medicine
    Journal - Association of Official Analytical Chemists
  • 1979
TLDR
A collaborative study was undertaken to determine the interlaboratory reproducibility of this microbial mutagenicity assay and found that two chemicals gave positive results in 2 laboratories; the same 2 chemicals were negative when tested in the third laboratory.
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