Mutagenicity of some commercially available nitro compounds for Salmonella typhimurium.

@article{Chiu1978MutagenicityOS,
  title={Mutagenicity of some commercially available nitro compounds for Salmonella typhimurium.},
  author={Clement Shui Wah Chiu and Lanfong H. Lee and Ching Yung Wang and George T. Bryan},
  journal={Mutation research},
  year={1978},
  volume={58 1},
  pages={
          11-22
        }
}
Benzoyl chloride and 53 commercially available aromatic heterocyclic and aliphatic nitro compounds were tested for mutagenicity in Salmonella typhimurium TA98 and TA100. 34 of 53 nitro compounds (64%) were mutagenic, 4 in TA100 only, 15 in TA98 only, and 15 in both strains. 13 of the heterocyclic derivatives of pyridine, indole, indazole, quinoline, and benzimidazole were mutagenic. 21 of 34 mutagenic nitro compounds were bactericidal. Nitromethane was the only aliphatic tested and was not… CONTINUE READING
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