Mutagenicity of chili extract and capsaicin in short-term tests.

  title={Mutagenicity of chili extract and capsaicin in short-term tests.},
  author={M. Nagabhushan and Sumati V. Bhide},
  journal={Environmental mutagenesis},
  volume={7 6},
Vanillin, capsaicin and chili extracts were tested for mutagenicity in Salmonella typhimurium histidine-deficient tester strains TA 98, TA 100, TA 1535, TA 1537, and TA 1538. Vanillin was nonmutagenic, whereas chili extract and capsaicin were mutagenic with metabolic activation. Capsaicin, an active component of chili extract, was the more potent mutagen. The positive samples were also tested in two mammalian test systems: the micronucleus test and the 8-azaguanine-resistant mutagenesis assay… CONTINUE READING
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