Mutagenicity of an aged gasworks soil during bioslurry treatment

  title={Mutagenicity of an aged gasworks soil during bioslurry treatment},
  author={Christine L. Lemieux and Krista D Lynes and Paul A. White and Staffan Lundstedt and Lars G. {\"O}berg and Iain B. Lambert},
  journal={Environmental and Molecular Mutagenesis},
  pages={404 - 412}
This study investigated changes in the mutagenic activity of organic fractions from soil contaminated with polycyclic aromatic hydrocarbons (PAHs) during pilot‐scale bioslurry remediation. Slurry samples were previously analyzed for changes in PAH and polycyclic aromatic compound content, and this study examined the correspondence between the chemical and toxicological metrics. Nonpolar neutral and semipolar aromatic fractions of samples obtained on days 0, 3, 7, 24, and 29 of treatment were… 

Aerobic Bioremediation of PAH Contaminated Soil Results in Increased Genotoxicity and Developmental Toxicity.

The formation of more polar and toxic polycyclic aromatic hydrocarbon (PAH) transformation products is one of the concerns associated with the bioremediation of PAH-contaminated soils and the increased toxicity measured postbiOREmediation is likely due to hydroxylated and carboxylated transformation products of the 3- and 4-ring PAHs.

Evaluating the effects of bioremediation on genotoxicity of polycyclic aromatic hydrocarbon-contaminated soil using genetically engineered, higher eukaryotic cell lines.

Investigating changes in the toxicity and genotoxicity of PAH-contaminated soil from a former manufactured-gas plant site before and after two simulated bioremediation processes found that column treatment induced DNA damage types that were not observed in untreated soil.

Nontarget Analysis Reveals a Bacterial Metabolite of Pyrene Implicated in the Genotoxicity of Contaminated Soil after Bioremediation.

This work pursued a nontarget analytical approach combining effect-directed analysis (EDA) and metabolite profiling to compare extracts of PAH-contaminated soil from a former manufactured-gas plant site before and after treatment in a laboratory-scale aerobic bioreactor, and found a compound purified from soil extracts was determined to be genotoxic.

Improving Polycyclic Aromatic Hydrocarbon Biodegradation in Contaminated Soil Through Low-Level Surfactant Addition After Conventional Bioremediation.

Research using submicellar doses of surfactant as a second-stage treatment step is limited and these findings can inform the design of bioremediation systems at field sites treating soil contaminated with PAHs and other hydrophobic contaminants that have low bioaccessibility.

Recent Advances in the Study of the Remediation of Polycyclic Aromatic Compound (PAC)-Contaminated Soils: Transformation Products, Toxicity, and Bioavailability Analyses.

Polycyclic aromatic compounds (PACs) encompass a diverse group of compounds, often found in historically contaminated sites. Different experimental techniques have been used to remediate

Mammalian cell line-based bioassays for toxicological evaluation of landfill leachate treated by Pseudomonas sp. ISTDF1

The present work examined the efficiency of an earlier reported Pseudomonas sp.



Degradation and formation of polycyclic aromatic compounds during bioslurry treatment of an aged gasworks soil

Investigation of the relative degradation rates of polycyclic aromatic compounds in contaminated soil found that low molecular weight PAHs and heterocyclics were degraded faster than the high molecular weight compounds, while oxy-PAHs degraded more slowly than the parent compounds, suggesting that they were formed during the treatment or that they are more persistent.

Bioassay-directed fractionation and chemical identification of mutagens in bioremediated soils.

The CMP and LT processes were the most effective and least toxic bioremediation procedures based on mutagenic potency and chemical analysis.

Mutagenic potential of environmental samples before and after remediation of a solvent-contaminated site

Soil, sediment, and paint sludge samples were collected during a 4-year period from an abandoned solvent recovery site prior to and after site remediation. Samples were sequentially extracted with

Toxicity and genotoxicity enhancement during polycyclic aromatic hydrocarbons biodegradation

It is concluded that when degradation is incomplete, the potential exists for toxicity and genotoxicity enhancement, with the latter hazard not always predictable by short-term toxicity assays.

Mutagenicity of polycyclic aromatic compounds (PAC) identified in source emissions and ambient air.

Assessing Detoxification and Degradation of Wood Preserving and Petroleum Wastes in Contaminated Soil

This study was undertaken to evaluate in-situ soil bioremediation processes, including degradation and detoxification, for two types of wood preserving wastes and two types of petroleum refining

Mutagens in contaminated soil: a review.

Genotoxicity is unrelated to total concentration of priority carcinogenic polycyclic aromatic hydrocarbons in soils undergoing biological treatment.

The data show that genotoxicity of contaminated soils may be unrelated to the concentration of carcinogenic PAHs because of aging or new mutagens formed during biological treatment.

The influence of application rate on the bacterial mutagenicity of soil amended with municipal sewage sludge.

Effect of petrochemical sludge concentrations on changes in mutagenic activity during soil bioremediation process

The persistence of the direct mutagenic activity of the sludge‐amended soils was related to theSludge concentration, whereas the indirect Mutagenic persistence was relatedto the relationship between easily degradable hydrocarbons and polynuclear aromatic hydroCarbons concentration and independent from the initial application rate.