Mutagenicity of a series of hexacoordinate cobalt(III) compounds.

@article{Schultz1982MutagenicityOA,
  title={Mutagenicity of a series of hexacoordinate cobalt(III) compounds.},
  author={Pamela Narcille Schultz and Graham Warren and C Kosso and Shirley Rogers},
  journal={Mutation research},
  year={1982},
  volume={102 4},
  pages={
          393-400
        }
}
15 cobalt(III) compounds have been tested for DNA-damaging capabilities using an E. coli differential repair assay and for mutagenicity in strains of Salmonella typhimurium. 4 of these compounds were active in both systems. Although the general ligand requirements for genetic activity of cobalt(III) appear to closely parallel those of chromium(III) and rhodium(III), the genetic activity of cobalt compounds seems particularly dependent upon the structure of the ligands coordinated about the… CONTINUE READING

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