Mutagenicity of 7,12-dimethylbenz[a]anthracene and some other aromatic mutagens in Drosophila melanogaster.

@article{Zijlstra1984MutagenicityO7,
  title={Mutagenicity of 7,12-dimethylbenz[a]anthracene and some other aromatic mutagens in Drosophila melanogaster.},
  author={Jaap A. Zijlstra and Ekkehart W. Vogel},
  journal={Mutation research},
  year={1984},
  volume={125 2},
  pages={
          243-61
        }
}
The optimal conditions for mutagenesis studies with DMBA and some other aromatic carcinogens in Drosophila were investigated in detail. The results presented in this paper indicate the following. The mutagenic effectiveness of DMBA is dependent on the route of administration, injection being far more effective when compared with feeding. The choice of the solvent is a crucial experimental condition. DMBA, when dissolved in oil/DMF, is ineffective whereas a special fat emulsion of DMBA gives… CONTINUE READING
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