Mutagenicity and safety evaluation of the water extract of Camellia oleifera Abel.

@article{Zhang2011MutagenicityAS,
  title={Mutagenicity and safety evaluation of the water extract of Camellia oleifera Abel.},
  author={Ying Zhang and Qiuping Chen and Xiaowei Luo and Tiantian Dai and Baiyi Lu and Jianfu Shen},
  journal={Journal of food science},
  year={2011},
  volume={76 3},
  pages={
          T84-9
        }
}
UNLABELLED The purpose of this study was to evaluate the mutagenicity and safety of water extract of the fruit hull of Camellia oleifera Abel (WECO), which was prepared using hot-reflux method. The oral maximum tolerated dose (MTD) of WECO was above 20 g/kg body weight both in rats and in mice, which can be regarded as virtually nontoxic. No mutagenicity was found in Ames test, mouse bone marrow cell micronucleus test and mouse sperm abnormality test. In the subacute study, the SD rats were… CONTINUE READING

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