Mutagenicity and genotoxicity of nitroarenes. All nitro-containing chemicals were not created equal.

@article{Rosenkranz1983MutagenicityAG,
  title={Mutagenicity and genotoxicity of nitroarenes. All nitro-containing chemicals were not created equal.},
  author={Herbert S. Rosenkranz and Robin Mermelstein},
  journal={Mutation research},
  year={1983},
  volume={114 3},
  pages={217-67}
}
The nitrated polycyclic aromatic hydrocarbons constitute a group of chemicals of environmental concern which display a broad spectrum of mutagenic, genotoxic and carcinogenic properties. Some members of the group are the most potent direct-acting bacterial mutagens while others exhibit low levels of potencies which require metabolic activation mixtures. Bacterial mutagenicity is dependent upon reduction of the nitro function. In mammalian cell systems the genetic and genotoxic effects of these… CONTINUE READING
71 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 71 extracted citations

Similar Papers

Loading similar papers…