Mutagenic effect of BUdR in diploid human fibroblasts.


It has only recently been possible to demonstrate the expected mutagenic effect of 5-bromodeoxyuridine (BUdR) in heteroploid hamster cells in culture. We have now extended this observation to diploid human fibroblasts utilizing techniques adapted from the work of Albertini and DeMars on X-ray mutagenesis at the hypoxanthine-guanine phosphoribosyltransferase… (More)


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@article{Stark1974MutagenicEO, title={Mutagenic effect of BUdR in diploid human fibroblasts.}, author={Rosemary M Stark and J W Littlefield}, journal={Mutation research}, year={1974}, volume={22 3}, pages={281-6} }