Mutagenic and cytotoxic activity of an isocoumarin (Paepalantine) isolated from Paepalanthus vellozioides.

Abstract

A new isocoumarin with antimicrobial activity was isolated from Paepalanthus vellozioides (a native Brazilian plant) and called paepalantine. This study was carried out to assess the mutagenic activity of this new agent in assays with Salmonella typhimurium TA100, TA98, and TA102 and in Chinese hamster ovary (CHO) cell cultures, as well as cytotoxicity to… (More)

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@article{Varanda1997MutagenicAC, title={Mutagenic and cytotoxic activity of an isocoumarin (Paepalantine) isolated from Paepalanthus vellozioides.}, author={Eliana Aparecida Varanda and Maria Stella Gonçalves Raddi and Felipe A. Dias and Maur{\'i}cio C. Ara{\'u}jo and S C Gibran and Catarina Satie Takahashi and Wagner Vilegas}, journal={Teratogenesis, carcinogenesis, and mutagenesis}, year={1997}, volume={17 2}, pages={85-95} }