Mutagenic activity from nitrosation of oligoamines.

  title={Mutagenic activity from nitrosation of oligoamines.},
  author={Michael A. Murphey-Corb and Hwai Loong Kong and Malissa Murray},
  journal={Environmental mutagenesis},
  volume={5 1},
To determine structural features necessary for the production of direct mutagenic activity from oligoamine-nitrate reaction mixtures, we systematically tested a group of aliphatic amine substrates for comutagenic action with nitrite. The ability to react with nitrite and form direct-acting mutagenic derivatives was common to a reasonably well defined class… CONTINUE READING