Mutagenesis studies on cultured mammalian cells. The sensitivity of the asparagine-requiring phenotype to several chemical agents.

Abstract

The effect of several chemical agents on the mutation frequency from asparagine dependence to asparagine independence has been studied in Jensen sarcoma cells. It was found that ethylmethanesulfonate brought about a dramatic exponential increase, while nitrosoguanidine was not lighly effective as a mutagen, causing only a modest increase in mutation… (More)

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@article{Morrow1976MutagenesisSO, title={Mutagenesis studies on cultured mammalian cells. The sensitivity of the asparagine-requiring phenotype to several chemical agents.}, author={Jay S. Morrow and Morgan D S Prickett and Stephanie Fritz and David M Vernick and Dennis Deen}, journal={Mutation research}, year={1976}, volume={34 3}, pages={481-8} }