Mutagen-directed attenuation of Rift Valley fever virus as a method for vaccine development.

@article{Caplen1985MutagendirectedAO,
  title={Mutagen-directed attenuation of Rift Valley fever virus as a method for vaccine development.},
  author={H S Caplen and Clarence J. Peters and David H. L. Bishop},
  journal={The Journal of general virology},
  year={1985},
  volume={66 ( Pt 10)},
  pages={2271-7}
}
Serial mutagenesis with 5-fluorouracil has been employed to derive an attenuated strain of Rift Valley fever virus for use as a live virus vaccine. 

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A simple method of est imating fifty per cent end points

  • L. J. REED, O. MUENCH
  • American Journal of Hygiene
  • 1938
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