Mutações do Gene do Receptor Sensível ao Cálcio Extracelular e Suas Doenças Associadas

  title={Mutaç{\~o}es do Gene do Receptor Sens{\'i}vel ao C{\'a}lcio Extracelular e Suas Doenças Associadas},
  author={Kozue Miyashiro and Omar Magid Hauache},
Mutations of the Extracellular Calcium-Sensing Receptor Gene and its Associated Diseases. The extracellular calcium-sensing receptor (CaR) is a G protein coupled receptor (GPCR) that plays a key role in the regulation of extracellular calcium homeostasis, being expressed in all tissues related to this control (parathyroid glands, thyroid C-cells, kidneys, intestine and bones). The cloning of the CaR was immediately followed by the association of genetic human diseases with inactivating and… CONTINUE READING


Publications referenced by this paper.

Physiology and pathophysiology of the extracellular calcium sensing receptor

  • EM Brown
  • Am J Med
  • 1999
Highly Influential
10 Excerpts

Putative mammalian taste receptors: a class Receptor Sensível ao Cálcio

  • MA Hoon, E Adler, J Lindemeier, JF Battey, NJP Ryba, CS. Zuker
  • Extracelular Miyashiro & Hauache
  • 2002
2 Excerpts

Treatment of hypercalcemia secondary to Receptor Sensível ao Cálcio

  • MT Collins, MC Skarulis, JP Bilezikian, SJ Silverberg, AM Spiegel, SJ. Marx
  • Extracelular Miyashiro & Hauache
  • 2002
1 Excerpt

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