MutY-glycosylase: an overview on mutagenesis and activities beyond the GO system.

Abstract

MutY is a glycosylase known for its role in DNA base excision repair (BER). It is critically important in the prevention of DNA mutations derived from 7,8-dihydro-8-oxoguanine (8-oxoG), which are the major lesions resulting from guanine oxidation. MutY has been described as a DNA repair enzyme in the GO system responsible for removing adenine residues… (More)
DOI: 10.1016/j.mrfmmm.2014.08.002

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