MutL homologs in restriction-modification systems and the origin of eukaryotic MORC ATPases

Abstract

The provenance and biochemical roles of eukaryotic MORC proteins have remained poorly understood since the discovery of their prototype MORC1, which is required for meiotic nuclear division in animals. The MORC family contains a combination of a gyrase, histidine kinase, and MutL (GHKL) and S5 domains that together constitute a catalytically active ATPase… (More)
DOI: 10.1186/1745-6150-3-8

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Cite this paper

@article{Iyer2008MutLHI, title={MutL homologs in restriction-modification systems and the origin of eukaryotic MORC ATPases}, author={Lakshminarayan M. Iyer and Saraswathi Abhiman and L. Aravind}, journal={Biology Direct}, year={2008}, volume={3}, pages={8 - 8} }