Mussels increase xenobiotic (azaspiracid) toxicity using a unique bioconversion mechanism.

  title={Mussels increase xenobiotic (azaspiracid) toxicity using a unique bioconversion mechanism.},
  author={Daniel O'Driscoll and Zuzana {\vS}krab{\'a}kov{\'a} and John O'Halloran and Frank F N A M van Pelt and Kevin J James},
  journal={Environmental science & technology},
  volume={45 7},
Azaspiracid Poisoning (AZP) is a human toxic syndrome which is associated with the consumption of bivalve shellfish. Unlike other shellfish, mussels contain a large array of azaspiracid analogs, many of which are suspected bioconversion products. These studies were conducted to elucidate the metabolic pathways of azaspiracid (AZA1) in the blue mussel (Mytilus edulis) and revealed that the main biotransformation product was the more toxic demethyl analog, AZA3. To elucidate the mechanism of this… CONTINUE READING
7 Citations
33 References
Similar Papers


Publications citing this paper.
Showing 1-7 of 7 extracted citations


Publications referenced by this paper.
Showing 1-10 of 33 references

The development of a rapid method for the isolation of four azaspiracids for use as reference materials for quantitative LC - MS / MS methods

  • K. O’Callaghan, C. Moroney, B. Hamilton, K. J. James, A. Furey
  • Anal . Bioanal . Chem .
  • 2010

Azadinium spinosum gen . et sp . nov . ( Dinophyceae ) identi fi ed as a primary producer of azaspiracid toxins

  • U. Tillmann, M. Elbrchter, B. Krock, U. John, A. Cembella
  • Eur . J . Phycol .
  • 2009

Similar Papers

Loading similar papers…